Tumor Molecular Cytogenetics in Head and Neck Cancer
نویسندگان
چکیده
منابع مشابه
Molecular profiling of tumor progression in head and neck cancer.
OBJECTIVE To assess gene expression changes associated with tumor progression in patients with squamous cell carcinoma of the oral cavity. DESIGN A microarray containing 17 840 complementary DNA clones was used to measure gene expression changes associated with tumor progression in 9 patients with squamous cell carcinoma of the oral cavity. Samples were taken for analysis from the primary tum...
متن کاملQuality of life in head and neck cancer patients
Quality of life in head and neck cancer patients
متن کاملMolecular genetics of head and neck cancer.
BACKGROUND Head and neck cancers have multiple genetic abnormalities that influence tumor behavior and may be useful in developing new treatments. METHODS Genetic alterations implicated in head and neck cancer oncogenesis and behavior are reviewed, and molecular techniques for detection and treatment are evaluated. RESULTS The large number of genetic changes present in head and neck cancer ...
متن کاملMalignancy detection by molecular cytogenetics in clinically normal mucosa adjacent to head and neck tumors.
OBJECTIVE To identify the potential use of chromosome imbalances as biomarkers for tumorigenesis in head and neck squamous cell carcinoma (HNSCC) by fluorescence in situ hybridization (FISH). DESIGN In this case-control study, chromosome copy numbers were assessed in dual-target, dual-color FISH assays using DNA probes specific for 14 human chromosomes (1, 2, 3, 6, 7, 8, 9, 10, 11, 12, 15, 17...
متن کاملCirculating tumor cells in head and neck cancer: A review
Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness. Circulating tumor cells (CTCs) have been identified as a potential marker for early metastatic di...
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ژورنال
عنوان ژورنال: Journal of Clinical Otolaryngology Head and Neck Surgery
سال: 1996
ISSN: 1225-0244,2713-833X
DOI: 10.35420/jcohns.1996.7.1.63